21 Largest Generic Drug Companies (2023)

FAQs

Who are the biggest generic drug manufacturer? ›

Revenues of leading global generics manufacturers 2020

With a revenue of 9.5 billion U.S. dollars, Sandoz was the global leading generics manufacturer in 2020. The second ranked company Teva generated 9.3 billion U.S. dollars that year.

Teva. No company has felt the stagnation of the generic drugs market quite like Teva. While its $8.99 billion haul topped the industry in 2021, last year marked the company's fifth straight generics sales decline.

Teva is the world's leading generic drug producer. In October 2020- Teva launched first generic versions of HIV-1 treatment Truvada and Atripla. In 2020- Teva has generated revenue of $9.31B from its generic segment.

Teva Pharmaceutical Industries is the world's biggest generic drug manufacturing company based on 2015 revenue.

"In contrast to brand-name drugs, which are largely made in Europe, generic products and their API are typically made in Asian countries such as India, China, Japan, Singapore, and others."

The generic has to have the same active ingredients and in the same amount as the original. But the other ingredients in the pill, such as fillers, can be different. And that can affect how quickly the medication gets absorbed by your body, Cooperman explains.

There are 365 Generic Pharmaceutical Manufacturing businesses in the US as of 2022, a decline of -2.9% from 2021. Has the number of Generic Pharmaceutical Manufacturing businesses in the US grown or declined over the past 5 years?

Which is better Teva or Mylan? ›

Our comparative analysis shows that Mylan holds an edge over Teva when considering price performance and ESP. However, when considering EV/EBITDA ratios, gross margins, estimate revisions and a more comprehensive look at its previous earnings performance, Teva is clearly a better stock.

1. Pfizer Inc (US) Pfizer is the world's largest research-based pharmaceutical company. Its research headquarters are located in Groton, Connecticut, America.

Teva is the Hebrew word for nature (Hebrew: טבע, "nature").

Teva Pharmaceutical Industries Ltd is a Israeli-based pharmaceutical company. The Company operates through three segments: North America, Europe and International Markets. Each business segment manages entire product portfolio in its region, including generics, specialty and over-the-counter (OTC) products.

Teva sildenafil is a generic version of Viagra that treats erectile dysfunction (ED) and heart conditions like pulmonary arterial hypertension (PAH). Viagra is so popular that its name has become synonymous with ED treatment — just like Ziploc has with plastic bags.

In case you're wondering, the league tables look like this: the US leads in the discovery of approved drugs, by a wide margin (118 out of the 252 drugs).

Industry. As of 2019, several major companies traditionally dominate the generic drugs market, including Teva, Mylan, Novartis' Sandoz, Amneal and Endo International.

The Deerfield, Illinois-based company, which operates the Walgreens and Duane Reade pharmacies in the United States and Boots in Britain, has more than 18,750 stores in over 25 countries. It has an agreement to source branded and generic drugs from AmerisourceBergen in the United States.

Where does CVS get their drugs? ›

McKesson primarily supplies CVS Health's Caremark mail and specialty pharmacies.

Many hospitals that take advantage of this higher reimbursement system utilize a large number of generic drugs in their in-hospital pharmacies. In fact, it has been reported that the rate of generic drug usage by in-hospital patients has been increasing [16].

Cons of generic drugs:

Patients perceive them as inferior to branded drugs. If they're not co-formulated, higher pill burdens may deter adherence. Overall co-payments for a regimen could result in higher costs to patients. They may have a different pill size/color when generic suppliers change.

Though the names are different, generic and brand-name drugs work the same. According to the FDA, generic drugs are just as effective as their branded counterparts. Generic name drugs typically cost about 80% to 85% less than branded drugs.

Generic medicines work the same as brand-name medicines

A generic medicine is required to be the same as a brand-name medicine in dosage, safety, effectiveness, strength, stability, and quality, as well as in the way it is taken. Generic medicines also have the same risks and benefits as their brand-name counterparts.

Pfizer Completes Transaction to Combine Its Upjohn Business with Mylan. NEW YORK--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) announced today that it has completed the transaction to spin off its Upjohn Business and combine it with Mylan N.V. to form Viatris Inc.

Pfizer is planning to spin-out its generic drugs business into a joint venture with Mylan, in a deal that was due to be completed in the middle of the year. Now that the FTC has formally cleared the merger, the new firm, Viatris, will become a generics giant, with Pfizer owning 57% and Mylan owning 43%.

The deal allows Pfizer a greater focus on the innovative drug franchise after its spinoff of its consumer health portfolio into a joint venture with GlaxoSmithKline. Mylan gains Upjohn's global footprint, especially in China.

Johnson & Johnson

And, despite a run by Pfizer in 2021, J&J was able to hold off its Big Pharma rival and retain the top spot.

Merck! The oldest pharmaceutical company in the world was founded in 1668, in Germany. Friedrich Jacob Merck (1621—1678) acquired a pharmacy called the Engel-Apotheke. Today is still in the possession of the family and open to the public in the heart of Darmstadt, Germany.

Which country exports the most drugs? ›

In 2020, the top exporters of Pharmaceutical products were Germany ($99.5B), Switzerland ($77.9B), Ireland ($67B), United States ($60.4B), and Belgium ($44.4B). In 2020, the top importers of Pharmaceutical products were United States ($134B), Germany ($60.5B), Switzerland ($39B), Belgium ($35.7B), and China ($30.8B).

Due to the large number of generic drugs dispensed – approximately 89 percent of all prescriptions in the U.S. – even a small margin on a drug can result in a large source of revenue due to the volume of product dispensed. This same dynamic leaves generic manufacturers with relatively little negotiating power.

Once a new drug is approved, the FDA provides a guaranteed period during which a generic version cannot be approved, regardless of the time remaining on the new drug's patent. This regulatory exclusivity typically runs for at least six years for new drugs.

A generic drug is a medication created to be the same as an already marketed brand-name drug in dosage form, safety, strength, route of administration, quality, performance characteristics, and intended use.

Teva ponies up $420M to settle with investors who said company hid price-fixing scheme. Generics giant Teva will pay $420 million to settle a lawsuit with shareholders who said the company concealed a price-fixing scheme that allowed it to raise prices on some drugs by more than 1,000%.

A Mylan factory sits in a Maharashtra Industrial Development Corp. area in Nashik, Maharashtra, India. India is the world's largest exporter of generic drugs, making almost 40 percent of all new generics the FDA approved in 2018 through October.

What Is Mylan Birth Control? Mylan birth control pills are the generic brand of Ortho Tri-Cyclen. The medication is a blend of female hormones (estrogen and progestin) that prevent the release of an egg from the ovaries (ovulation).

Pfizer, takes the top spot in 2022, rising from sixth in 2021. Pfizer, specialises in the development of medicines and vaccines across a wide range of disciplines including immunology, oncology, cardiology and neurology.

Pfizer, a GSK partner, intends to sell off its stake in the consumer health company when the de-merger occurs. GSK's consumer health business has been a joint venture with Pfizer.

Who is the main shareholder of Pfizer? ›

For all regulated drugs, China has 230 (13 percent) of the API manufacturing facilities, while the United States has 510 (28 percent), and the rest of the world has 1048 (59 percent).

The primary difference between biopharmaceuticals and traditional pharmaceuticals is the method by which the drugs are produced: The former are manufactured in living organisms such as bacteria, yeast and mammalian cells, whereas the latter are manufactured through a series of chemical synthesis.

Johnson & Johnson. Johnson and Johnson is one of the United States' oldest pharmaceutical companies. It began as a medical and surgical equipment producer.

"In contrast to brand-name drugs, which are largely made in Europe, generic products and their API are typically made in Asian countries such as India, China, Japan, Singapore, and others."

Industry. As of 2019, several major companies traditionally dominate the generic drugs market, including Teva, Mylan, Novartis' Sandoz, Amneal and Endo International.

There are 365 Generic Pharmaceutical Manufacturing businesses in the US as of 2022, a decline of -2.9% from 2021. Has the number of Generic Pharmaceutical Manufacturing businesses in the US grown or declined over the past 5 years?

Our comparative analysis shows that Mylan holds an edge over Teva when considering price performance and ESP. However, when considering EV/EBITDA ratios, gross margins, estimate revisions and a more comprehensive look at its previous earnings performance, Teva is clearly a better stock.

Where does Walgreens get their generic drugs? ›

The Deerfield, Illinois-based company, which operates the Walgreens and Duane Reade pharmacies in the United States and Boots in Britain, has more than 18,750 stores in over 25 countries. It has an agreement to source branded and generic drugs from AmerisourceBergen in the United States.

McKesson primarily supplies CVS Health's Caremark mail and specialty pharmacies.

The generic has to have the same active ingredients and in the same amount as the original. But the other ingredients in the pill, such as fillers, can be different. And that can affect how quickly the medication gets absorbed by your body, Cooperman explains.

The same generic drug, made by a different manufacturer, can indeed look different. Due to certain patent laws that govern brand-name medications, generic drug manufacturers are not allowed to copy how a brand-name pill looks in terms of its shape, its color and its size.

Generic medicines tend to cost less than their brand-name counterparts because they do not have to repeat animal and clinical (human) studies that were required of the brand-name medicines to demonstrate safety and effectiveness.

Generic drugs do not need to contain the same inactive ingredients as the brand name product. However, a generic drug can only be marketed after the brand name drug's patent has expired, which may take up to 20 years after the patent holder's drug is first filed with the U.S. Food and Drug Administration (FDA).

Due to the large number of generic drugs dispensed – approximately 89 percent of all prescriptions in the U.S. – even a small margin on a drug can result in a large source of revenue due to the volume of product dispensed. This same dynamic leaves generic manufacturers with relatively little negotiating power.

A generic drug is a medication created to be the same as an already marketed brand-name drug in dosage form, safety, strength, route of administration, quality, performance characteristics, and intended use.

Teva ponies up $420M to settle with investors who said company hid price-fixing scheme. Generics giant Teva will pay $420 million to settle a lawsuit with shareholders who said the company concealed a price-fixing scheme that allowed it to raise prices on some drugs by more than 1,000%.

Where are Mylan generics made? ›

A Mylan factory sits in a Maharashtra Industrial Development Corp. area in Nashik, Maharashtra, India. India is the world's largest exporter of generic drugs, making almost 40 percent of all new generics the FDA approved in 2018 through October.

What Is Mylan Birth Control? Mylan birth control pills are the generic brand of Ortho Tri-Cyclen. The medication is a blend of female hormones (estrogen and progestin) that prevent the release of an egg from the ovaries (ovulation).